The Elephant in the Room in the times of Corona

Art by Anna Deveaux, M.Sc., Canva

Recent reports confirmed that UK Prime Minister Boris Johnson denied saying he would rather see bodies piled on the streets than another lockdown. Billions across the world struggle to cope financially, mentally, and psychologically. Sensibly, experts worry in silence whether the continued pandemic confinement may irreparably damage the mental health of millions in the UK and the world.

Prior to the COVID19 disaster and according to the official statistics, 284 million people globally were already struggling with anxiety and another 300 million with addiction. Pre-pandemic numbers were on the rise compared to two decades ago. The twenty-year increase is significant…


Ten milestones including Vladimir Putin, Lars Bildman, and Nexium, that make me feel uneasy

Pascal Soriot in March 2019, during a meeting in Moscow with Vladimir Putin.

The beginning

The twenty-two-year history of AstraZeneca is an interesting path with cases of fraud, misrepresentation, and sexual harassment charges.

In 1996, three years before Astra met Zeneca and merged into AstraZeneca, Lars Bildman, the former CEO of Astra, was accused of sexual harassment and gross misconduct. Swedish-born Lars Bildman, also known as drunk Swede, apparently concocted tales of a conspiracy involving KGB back in 1996. Or was there a real conspiracy?

2001 — Nexium

Nexium was introduced as a new tradename of an old drug Omeprazole. AstraZeneca (AZN) marketed Omeprazole (long approved for medical use) as a new drug, Esomeprazole. …


Psilocybin may soon be legally available for young and old

Art by Anna Deveaux

Did you know that psychedelics acceptance is just around the corner? Robust and durable beneficial mind-altering properties of single or few-doses psilocybin can be used respectfully by carefully selected young and old individuals.

Let's be clear. Some botanicals including cannabis are currently still listed on Schedule 1 of the United Nations Convention on Psychotropic Substances (1971). Scheduled substances may or may not lack therapeutic effects or may have a high potential for abuse/dependence, and may cause serious adverse effects. Psilocybe mushrooms, on the other hand, are not scheduled under the UN Convention, but many countries introduced specific laws to control…


Science is one step closer to reverse the damage of chronic stress

Canva

Stress is inevitable and suffering is universal, but victimhood is optional. The choice is yours, says Dr.Eger, who survived a concentration camp during World War II and reflected on life in her book. However, it is not easy to change the brain by using the brain itself. Stress causes maladaptive plasticity within the brain’s reward circuit. The mood and anxiety disorders affect one out of every six people in their lifetime and cost the United States economy an excess of $50 billion per year.

The recent good news stemmed from new studies attempting to tune the brain’s plasticity back to…


Should we call psilocybin a hallucinogen?

Should we call psilocybin a hallucinogen?
Medical misnomer or politically motivated lingo?
Medical misnomer or politically motivated lingo?

Let’s call a spade a spade, not a gardening tool

A misnomer is a name that is incorrectly or unsuitably applied. Terms in medicine are not just words; it’s sometimes life and death decision. The authorities confirmed the drug is safe, and FDA has approved it but the stigma is a powerful thing escpecially if the term is a misnomer.

Do we always name things correctly?

Stem cell transplantation

Hematopoietic stem cell transplantation, for example, is often called a bone marrow transplant. The latter is misleading and deleterious to the field of transplantation and real-world outcomes. Why? Transplantation success depends on the availability of cells from healthy…


What not to eat the evening before the vaccine shot?

Photo by Jay Wennington on Unsplash

No one knows what causes the side effects of the AstraZeneca vaccine. However, the estradiol/histamine theory may be a plausible explanation or at least a workable hypothesis.

The unfortunate death occurred in at least six women within two weeks of vaccination, with most of them being younger than 55 years old.


Some are born with status sensitivity and the taste for impulse buying

Photo by freestocks on Unsplash

How many of you still believe that narcissist is a victim of elusive childhood traumatic experience? One giant … lie? And here is why?

There is an increasing tendency toward narcissism among young adults worldwide, but the root causes are still obscure. Here are three scientifically-supported data points to consider why narcissism may be a genetic condition rather than the result of traumatic childhood upbringing.

Narcissists are geared toward the status

Investigators measured spontaneous facial muscle activity linked to positive affect (muscles responsible for smiling) and negative affect (muscles involved in frowning) in 123 children aged 8–13 participating in a game that involved status changes. The…


A single dose of psilocybin “couples” “uncoupled” brain networks

Art by @andeveaux

If consciousness is a state of being awake and aware, does it mean you are unconscious in your sleep?

For many years the majority of researchers considered dreamless sleep being equal to an unconscious state. Consciousness, however, is not a binary on/off state. Many states of consciousness are well known — dreamless sleep, REM sleep, sleepwalking, waking consciousness, vegetative state, and finally, a state of coma. More precisely, sleep is a state of reduced consciousness, and coma is the state of unconsciousness. …


better endure physical pain

Photo by JESHOOTS.COM on Unsplash

Men and women are created differently and they do experience pain differently. The debate is not about gender or equality. It is about Sex As a Biological Variable (SABV).

In 2016, the National Institute of Health (NIH) issued a policy introducing SABV in research. Humans and animals may be classified by sex, so are cells and tissues used in biomedical research.

Is pain processing equivalent in all sexes? In 1999, researchers became interested in gender/pain connection and formed a Special Interest Group on Sex, Gender, and Pain. Twenty years later, the topic is still controversial, but scientific discussions are advancing…


Including weight, heart diseases, and cancer risk

By Anna Deveaux, M.Sc., Canva

Surprise! One day psychedelics may become a new fitness trend.

The effects of therapeutic psychedelic treatment on mood disorders are receiving significant scientific attention. Psilocybin is currently being tested in several clinical trials for the treatment of mood disorders. However, arguably, even broader health benefits of classic psychedelics may include weight, cardiovascular disease, and cancer risk.

A groundbreaking new paper just published in March looked into the presumable broader health benefit of classic psychedelics. Three years of data, on over 170 000 people provided by the National Survey on Drug Use, was recently examined by a team of researchers from…

Anna Deveaux, M.Sc.

learner, writer, biotech investor, research translation, drug development, genetics. 4-lingual.

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